منابع مشابه
COPD phenotypes on computed tomography and its correlation with selected lung function variables in severe patients
BACKGROUND Computed tomography (CT) phenotypic characterization helps in understanding the clinical diversity of chronic obstructive pulmonary disease (COPD) patients, but its clinical relevance and its relationship with functional features are not clarified. Volumetric capnography (VC) uses the principle of gas washout and analyzes the pattern of CO2 elimination as a function of expired volume...
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The landmark study of Fletcher and Peto on the natural history of tobacco smoke-related chronic airflow obstruction suggested that decline in the forced expiratory volume in the first second (FEV(1)) in chronic obstructive pulmonary disease (COPD) is slow at the beginning, becoming faster with more advanced disease. The present authors reviewed spirometric data of COPD patients included in the ...
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n engl j med 364;1 nejm.org january 6, 2011 86 replacement therapy in patients with severe hereditary angioedema refractory to danazol prophylaxis. Transfusion 2009;49: 1987-95. 2. Bowen T, Cicardi M, Farkas H, Bork K, et al. 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema. Allergy Asthma Clin Immunol 2010;6:24. 3. Longhurst HJ, Farkas H...
متن کاملWhich pulmonary function tests best differentiate between COPD phenotypes?
We are still at the early phase of finding useful phenotypes in COPD that can guide therapy. However, in a simple sense, "sick patients die." Many phenotypic measurements of severity correlate with mortality in COPD: FEV(1), the ratio of inspiratory capacity to total lung capacity (IC/TLC), diffusing capacity of the lung for carbon monoxide (D(LCO)), 6-min walk distance, and maximum oxygen (O(...
متن کاملLung function decline in COPD trials.
STATEMENT OF INTEREST A statement of interest for P.L.P. Brand can be found at www.erj.ersjournals.com/misc/statements.shtml REFERENCES 1 Brand PLP, Baraldi E, Bisgaard H, et al. Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J 2008; 32: 1096–1110. 2 Lehtinen P, Ruohola A, Vanto T, Vuorinen T, Ruuskanen O, Jartti T. Predn...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2013
ISSN: 0954-6111
DOI: 10.1016/j.rmed.2013.08.037